PharmGKB
The Pharmacogenomics Knowledge Base (PharmGKB) is a comprehensive online resource that provides information about how human genetic variation affects response to medications. PharmGKB collects, curates, and disseminates knowledge about the impact of human genetic variation on drug responses, including dosing guidelines, drug labels with pharmacogenomic information, and primary literature. It serves as a valuable tool for researchers, clinicians, and students interested in pharmacogenomics.
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Domain Rating
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Citation Level
2000
English, etc
Website Key Features
Drug Labels
Provides FDA and other drug labels that contain pharmacogenomic information.
Clinical Guidelines
Offers clinical guidelines for drug dosing based on genetic information.
Pathway Visualizations
Visual representations of pharmacogenomic pathways to understand drug metabolism and effects.
Variant Annotations
Detailed annotations on genetic variants affecting drug response.
Literature Curation
Curated literature linking genetic variation to drug response.
Gene-Drug Relationships
Information on how specific genes affect responses to certain drugs.
Chemical-Disease Relationships
Data on how chemicals (drugs) interact with diseases at the genetic level.
Downloadable Data
Allows users to download pharmacogenomic data for research purposes.
Additional information
Funding
PharmGKB is funded by the National Institutes of Health (NIH) and other grants.
Collaborations
Works in collaboration with the Clinical Pharmacogenetics Implementation Consortium (CPIC) and other organizations.
Access
Free access to most resources, with some features requiring registration.
Updates
Regularly updated with new drug labels, clinical guidelines, and research findings.
Educational Resources
Provides educational materials and tutorials on pharmacogenomics.
HTTP headers
Security headers report is a very important part of user data protection. Learn more about http headers for pharmgkb.org